Penicillinase Resistant Penicillins in the Treatment of Surgical Staphylococcal Infections
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چکیده
منابع مشابه
Penicillinase-resistant Penicillins in the Treatment of Surgical Staphylococcal Infections.
although it has the advantage of being given orally, seems less effective, and ampicillin similarly. Comparative statistical evidence of the value of the various penicillins and of the antibiotics is not available, and would be difficult to obtain, but I have no personal doubt that at present in the acute infection methicillin and chloramphenical are the two most effective drugs. A major anxiet...
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The discovery of penicillinase-resistant penicillins is an important landmark in the history of antibacterial chemotherapy. Methicillin came into clinical use in 1960, and its value in the treatment of penicillin-resistant staphylococcal infection is now well established. The same is true of the isoxazolyl penicillins, oxacillin and cloxacillin, which came on to the scenes about a year later. N...
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The activities of some semisynthetic penicillins and cephalosporins have been tested against clinical strains of Staphylococcus aureus. The apparent activity in vitro varies with the method of testing used. Determination of MICs using light inocula fails to detect the destructive effect of penicillinase on the antibiotic. This was, however, demonstrated reproducibly by the use of a technique in...
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Heteroresistant (methicillin-resistant) and nonheteroresistant strains of Staphylococcus aureus were tested for their susceptibility to penicillinase-resistant penicillins at incubation temperatures of 37, 35, and 30 C. Susceptibilities were determined by agar dilution and by the standard Kirby-Bauer agar diffusion tests. Minimal inhibitory concentrations were higher at 35 and 30 C than at 37 C...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1964
ISSN: 0032-5473
DOI: 10.1136/pgmj.40.suppl.132